Table 3 : Polymeric micelles containing platinum-based drugs in clinical trials.


Micelle formulation Platinum based
drugs
Micelles Status MTD (mg/m2) References

NC-6004 cisplatin Poly(ethyleneglycol)-β-poly(glutamic acid) Phase I/II/III 120 85~89
NC-4016 DACHPt Poly(ethyleneglycol)-β-poly(glutamic acid) Phase I  -- 84,89~92

Ziora et al.Biochemical Compounds  2016 4:2DOI : 10.7243/2052-9341-4-2