Biochemical Compounds

Biochemical Compounds

ISSN 2052-9341
Database

Rare 6-deoxy-D-altrose from the folk medicinal mushroom Lactarius akahatsu

Masakuni Tako1,2*, Jyunpei Shimabukuro1,3, Wen Jiang1, Masashi Yamada3, Hideharu Ishida3 and Makoto Kiso3

*Correspondence: Masakuni Tako tako@agr.u-ryukyu.ac.jp

1. University of the Ryukyus, Department of Subtropical Bioscience and Biotechnology, Nishihara, Okinawa 903-0213, Japan.

Author Affiliations

2. University of the Ryukyus, Health and Longevity Research Laboratory, Integrated Innovation Research Centre, Nishihara, Okinawa 903-0213, Japan.

3. Gifu University, Department of Applied Bio-organic Chemistry, Gifu, Gifu 501-1193, Japan.

Abstract

A rare sugar, 6-deoxy-D-altrose, isolated from a polysaccharide extracted from an edible folk medicinal mushroom (Lactarius akahatsu) was identified using 1H and 13C-NMR including 2D-COSY and 2D-HSQC spectroscopy, and specific rotation. The 6-deoxy-sugar isolated from the acid hydrolysate of the polysaccharide extracted from L. akahatsu was involved in four anomeric isomers (α- and β-pyranose, and α-and β-furanose) in aqueous solution due to mutarotation. Almost all of the signals from the 1D (1H- and 13C-) and 2D (COSY and HSQC)-NMR spectra of the 6-deoxy-sugar agreed with the data from the authentic 6-deoxy-D-altrose. The specific rotation [α]589 of the 6-deoxy-sugar isolated from L. akahatsu was +17.6°. Thus, the 6-deoxy-sugar isolated from Lactarius akahatsu was identified as 6-deoxy-D-altrose.

Keywords: Lactarius akahatsu, folk medicinal mushroom, 6-deoxy-D-altrose, rare sugar, polysaccharide moiety

ISSN 2052-9341
Volume 1
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