Figure 1 : The effects of β-End and acetyl-β-End treatment on the AD-like skin lesions of NC/Nga mice.


Both SPF (a) and conventional mice (b) were treated with β-End or acetyl-β-End. Skin symptoms were apparent in the conventional group, but not in the conventional mice treated with acetyl-β-End. The dermatitis score (c) was assessed at the rostral skin of the conventional  group based on the severity of erythema, hemorrhage and pilosis (0, none; 1, slight; 2, moderate; 3, severe). Thin sections of the skin specimens were stained with hematoxylin and eosin (d). The values are the means±SD derived from 10 animals. *, P<0.05 compared with  the no treatment conventional NC/Nga mice. Scale bar = 100 μm.

Hiramoto et al.Dermatology Aspects  2013 1:2DOI : 10.7243/2053-5309-1-2