Figure 3 : The effects of HAT inhibitor treatment on the AD-like skin lesion of NC/Nga mice.


Both SPF (a) and conventional (b) mice were exposed to either HAT inhibitor or β-End + HAT inhibitor treatment.
In the mice treated with β-End alone, the skin symptoms were reduced compared to the conventional mice with
no treatment (Figure 1b), but the symptoms were  increased in the mice with HAT inhibitor or β-End + HAT inhibitor
treatment. The dermatitis score (c) was assessed at the rostral skin of the conventional group based on the severity
of erythema, hemorrhage and pilosis (0, none; 1, slight; 2, moderate; 3, severe). The values are the means ± SD derived from 10 animals.

Hiramoto et al.Dermatology Aspects  2013 1:2DOI : 10.7243/2053-5309-1-2