Figure 1 : Evaluation of the severity of AD in SPF and conventional mice.

Macroscopic observations indicated that COEE reduced the severity of AD-like lesions in the NC/Nga mice in the
conventional group after 14 days of application.
Control: not exposed to any topical preparation.
COEE: treated with a cream containing Corchorus olitorius leaf extract excluding high molecular weight compounds.
BC: treated with the base cream.

Yokoyama et al.Dermatology Aspects  2014 2:3DOI : 10.7243/2053-5309-2-3