Figure 4 : The effects of COEE on the plasma IgE concentrations in NC/Nga mice
housed under conventional condition.

The topical application of COEE significantly reduced the IgE concentration under
conventional conditions. The data are presented as the means±S.D. (n=3 in each
SPF group, n=5 in each conventional group).
*: p<0.05, **: p<0.01 (one-way ANOVA followed by Tukey’s test).
Control: not exposed to any topical preparation.
COEE: treated with a cream containing Corchorus olitorius leaf extract excluding high
molecular weight compounds.
BC: treated with the base cream.

Yokoyama et al.Dermatology Aspects  2014 2:3DOI : 10.7243/2053-5309-2-3