Figure 8 : The results of the immunohistochemical analysis of the collagen type IV expression in the skin of NC/Nga mice.

(a) The collagen type IV expression in the conventional control and BC groups was decreased compared with that in the conventional COEE group.
Control: not exposed to any topical preparation.
COEE: treated with a cream containing Corchorus olitorius leaf extract excluding high molecular weight compounds.
BC: treated with the base cream. The scale bar represents 100 μm.
(b) Comparison of fluorescent intensity of collagen type IV among three groups in conventional conditions. a.u.: arbitrary unit, *: p<0.05,
**: p<0.01 (one-way ANOVA followed by Tukey’s test).

Yokoyama et al.Dermatology Aspects  2014 2:3DOI : 10.7243/2053-5309-2-3