2. Department of Nephrology and Clinical Transplantation, G.R. Doshi and K.M. Mehta Institute of Kidney diseases And Research Centre and Dr. H.L. Trivedi Institute of Transplantation Sciences, Ahmedabad, India.
Background: Adrenal ganglioneuromas in young adults are rare and ill-understood. We report an incidentally detected adrenal gland tumor diagnosed as ganglioneuroma (mature type).
Methods and result: Asian 33 years old male who presented with vomiting and epigastric pain for 2 months. USG and CTabdomen revealed well-defined rounded hypo-dense non-enhancing homogenous mass of left adrenal gland. Histopathology examination revealed a well-encapsulated benign tumor of mature ganglion cells and Schwann-like cells arranged in fascicles, staining strongly with NSE and s-100 proteins, with adjacent unremarkable adrenal cortex and medulla.
Conclusion: Ganglioneuromas (GN) of adrenal gland in adults are very rare and can have serendipitious presentation. We describe such a non-functional adrenal GN in a young male.
Keywords: Adrenal gland ganglioneuroma, cholecystitis, ganglion cells, catecholamines, neuroblastoma, mediastinum