2. Department of Emergency Medicine, Second Hospital of Jilin University, Norman Bethune College of Medicine, Ziqiang Street, Changchun, P.R.China.
3. Department of Obstetrics and Gynecology, Maternity and children hospital, Jilin Province, Liaoyuan city, Jilin province, P.R.China.
Objective: The purpose of this study is to understand the incidence, related factors, and the prognosis factors in order to avoid risk, proper method of diagnosis and treatment and reduce complications and provide the basis.
Methods: 85 Vulvar cancer (VC) patients treated in our hospital from 2002.10 to 2012.10 were collected and analyzed by retrospective comparative methods. SPSS19.0 application software was used for the statistical analysis. The clinical data are analyzed by chi-square and F test statistic methods. P<0.05 was a significant difference between the judgment standard.
Results: During 10 years, we treated 3391 cases of the primary malignant tumors including 85 VC cases; VC was 2.89% (85/3391). The age was between 24~88 years old, mean was 57.09±12.93 yrs. old, variable age (F=6.013, P=0.016<0.05). VC had seen more in rural than urban patients. By statistical analysis, region distribution in these two groups was remarkably different=4.16, P=0.045<0.05, but the urban proportion of patients in different years has no difference (Χ2=0.080, P=0.777).
Conclusion: The number of cases increased progressively in young age. VC patients were more in rural area than urban. High-risk groups Suggested doing regular physical exam. For long-term genital itching, genital tumor, genital ulcers, and other symptoms, should be alert to the possibility of VC. Preoperative diagnosis should be Colposcopic, biopsy in order to improve the accuracy of earlier diagnosis. Postoperative common complications are wound infection. Follow-up rate is low; It is difficult to say statistically survival rate is 5 years.
Keywords: Vulvar carcinoma, sentinel lymph node, risk factor, clinical manifestation, chemotherapy