Table 2 : Cytogenetic analysis of bone marrow cells.


Case 1 At the diagnosis of MDS-RCMD

  46,XX [10]
47,XX,-5,-7,+20,add(20)(q11.2)x2,add(22)(q11.2),+2mar [2]
48,XX,-5,-7,+20,add(20)(q11.2)x2,add(22)(q11.2),+3mar [8]

  At the transformation to PEL

  The following example chromosome is representative of the karyotype:
55,XX,+2,+add(2)(q21),+6,add(7)(p22),+12,-13,add(14)(p11.2),+15,+16,+17,+19,+21,add(22)(p11.2),+mar,dmin
54,XX,+X,+6,-7,add(7)(p22),+8,add(10)(q22),+12,add(14)(p11.2),+15,+16,+17,+19,add(22)(p11.2), +mar,dmin
54,XX,+2,-5,+6,add(7)(p22),+8,-9,+12,-13,add(14)(p11.2),+15,+19,+21,add(22)(p11.2),+4mar,dmin
100,XXXX,add(7)(p22)x2,+8,+8,-9,-9,-10,-11,+12,-13,-13,-13,add(14)(p11.2),+15,+add(15)(p11.2),+16,+16,
+17,+17,-18, +19,+19,+19,+20,+21+21,-22,-22,add(22)(p11.2)x2,+3mar,dmin

Case 2 At the diagnosis MDS-RA

  46,XX [20]

  At the transformation to PEL

  The following example chromosome is representative of the karyotype:
45,XX,t(1;9)(p10;p10),add(6)(p21.3),add(9)(p22),-10,add(19)(p13.3),add(21)(p11.2) [2]
81,XXX,-X,-3,-4,-9,-10,-10,-11,-12,add(12)(p11.2),-14,-16,-18,add(19)(p13.3)x2,-20,add(21)(p11.2)x2,+mar [2]

Mita et al.Hematology and Leukemia  2016 4:3DOI : 10.7243/2052-434X-4-3