Figure 4 : (a) Nuclear and metaphase FISH was performed using the LSI 5q EGR1/D5S23, D5S721 probes (5q31, orange; 5p15.2, green).

Arrows indicate both chromosome 5 homologs. The del (5)(q31) is missing the orange signal in both the metaphase and the nucleus. (b): Nuclear and metaphase FISH was performed using the LSI RUNX1/RUNX1T1 probes (8q21.3, orange; 21q22, green). Arrows indicate three copies of 8q21.3 in both the metaphase and the nuclei.

Liu et al.Hematology and Leukemia  2017 5:3DOI : 10.7243/2052-434X-5-3