Table 4 : Association of EMMPRIN (CD147) expression with different clinicopathological features of OSCC Cases.


Factor          EMMPRIN (CD147)  
Total (n %) Low expression Score
n (%)
High expression Score
n (%)
P-value

Age                         
                              
25-40 years 26 6(23) 20(77)  
41-60 years 50 26(52) 24(48)  0.04*
61-80 years 24 8(33) 16(67)  

Gender                           Male 58 20(34.5) 38(65.5)  
Female 42 20(48) 22(52) 0.19*

Site Buccal mucosa 34 8(23.5) 26(76.5)  
  Tongue 40 22(55) 18(45)  
  Gingiva 4 0(0) 4(100)  
Hard palate 2 2(100) 0(0)  0.01
Lower lip 12 6(50) 6(50)  
Upper lip 2 0(0) 2(100)  
Sub-mandibular  gland 6 2(33) 4(67)  

Clinical Presentation  Ulceration 48 22(46) 26(54)  
Swelling/lump 36 12(33) 24(67)  0.54†  
White patch  8 2(25) 6(75)  
Exophytic mass 8 4(50) 4(50)  

Histological subtype Conventional OSCC 92 36(39) 56(61)  0.27†
Papillary OSCC 6 4(67) 2(33)  
Oral Verrucous carcinoma 2 0(0) 2(100)  

Histological rade  Well Differentiated 64 34(53) 30(47)  
Moderately Differentiated 26 2(23) 20(77) 0.001*
Poorly Differentiated 10 0(0) 10(100)  

*Pearson Chi-square test †Fisher exact test.

Sahaf et al.Journal of Histology & Histopathology  2017 4:8DOI : 10.7243/2055-091X-4-8