Table 3 : Summary of mean admission levels* of MyD88-dependent (IL-8, TNF-α) and MyD88-independent (RANTES, IFN-β
cytokines and the ratio. These data are shown graphically in Figure 1.


  Gram-unknown mean Gram-unknown SEM Gram-negative mean Gram-negative SEM Gram-positive mean Gram-positive SEM **P-value

IFN-β 260.4 23.5 319.3 25.3 239.5 37.8 0.09
RANTES 2007.3 144.2 2229.5 268.6 1641.0 110.9 0.06
IL-8 153.1 41.7 184.3 58.2 235.0 52.5 0.52
TNF-α 5.1 0.6 4.8 1.4 7.4 0.7 0.11
Ratio*** 102.8 29 111.1 34.9 29.9 8.3 0.04

*All values are pg/mL of serum (except Ratio values, which is unitless).
**P values calculated by t-test (unequal variance).
***Calculated as [IFN-β] X [RANTES]/[IL-8] X [TNF-α].

Cowan et al.Research Journal of Infectious Diseases  2014 2:6DOI : 10.7243/2052-5958-2-6