Table 2: Characteristics and outcome of the patients hospitalized for new-onset diabetes, 1996-1997 vs 2008-2009. Patients with positive anti-GAD antibodies.


 

1996-1997

2008-2009

p


n

18

33

 

Men/women

9/9

25/8

NS

Age (yrs)

38±17

28±9

0.01

Body weight (kg)

61.3±13.8

62.7±7.6

NS

BMI(kg/m2)

22.0±4.2

21.0±2.6

NS

Glycaemia (mmol/L)

22.6±9.4

24.9±11.2

NS

HbA1C (%)

12.0±2.9

12.6±2.3

NS

Weight loss (kg/3months)

-6.3±4.8

-7.6±5.9

NS

Intercurrent disease (n)

6

5

NS

Corticosteroid use(n)

4

2

NS

Sweetened beverages (n)

5

11

NS

Serum C-peptide (nmol/L)

0.67±0.73

0.30±0.16

NS

Duration of hospitalization (d)

9.4±2.3

7.5±2.5

0.01

Capillary glucose level at discharge (mg/dL)

146±47

139±48

NS

Daily insulin dose at discharge (U)

34±22

51±27

0.03

Body weight 4 months later (kg)

65.9±13.7

70.1±10.8

NS

HbA1C 4 months later (%)

7.5±1.9

7.6±2.0

NS


Salandini et al.Journal of Diabetes Research and Clinical Metabolism  2012 1:12DOI : 10.7243/2050-0866-1-12