Table 3: Characteristics and outcome of the patients hospitalized for new-onset diabetes, 1996-1997 vs 2008-2009. Patients with negative anti-GAD antibodies.


 

1996-1997

2008-2009

p


n

31

46

 

Men/women

20/11

31/15

NS

Age (yrs)

48±16

45±14

NS

Body weight (kg)

66.1±12.1

78.1±24.1

0.02

BMI(kg/m2)

23.4±3.2

27.2±7.2

0.008

Glycaemia (mmol/L)

17.2±5.7

17.4±11.8

NS

HbA1C (%)

11.7±2.4

12.0±2.3

NS

Weight loss (kg/3months)

-6.4±4.2

-6.5±7.3

NS

Intercurrent disease (n)

7

20

NS (0.059)

Corticosteroid use(n)

3

3

NS

Sweetened beverages (n)

7

20

NS (0.059)

Serum C-peptide (nmol/L)

1.04±0.92

1.00±0.74

NS

Duration of hospitalization (d)

9.0±4.4

7.4±2.8

NS (0.062)

Capillary glucose level at discharge (mg/dL)

146±34

132±33

NS

Daily insulin dose at discharge (U)

20±21

29±25

NS

Body weight 4 months later (kg)

69.5±12.8

79.0±18.4

0.03

HbA1C 4 months later (%)

7.0±2.0

7.1±1.2

NS


Salandini et al.Journal of Diabetes Research and Clinical Metabolism  2012 1:12DOI : 10.7243/2050-0866-1-12