Table II: Changes of glycemic and other parameters.
A1)sitagliptin


 

baseline

3 month

p-values


FBS (mg/dl)

226.1+64.6

190.4+78.7

<0.002

HbA1c (%)

10.43+2.21

8.24+2.18

<0.00001

T-C (mg/dl)

227.1+42.2

221.2+42.3

n.s.

TG (mg/dl)

231.6+222.0

195.6+167.7

0.0651

HDL-C (mg/dl)

52.4+12.5

53.5+11.5

n.s.

nonHDL-C (mg/dl)

174.6+41.3

167.6+41.6

n.s.

LDL-C (mg/dl)

147.7+32.2

145.9+35.9

n.s.

FFA (eEq/l)

0.957+0.333

0.810+0.334

<0.05

UA (mg/dl)

5.11+1.42

5.67+1.35

<0.0005

insulin (µU/ml)

6.82+4.52

8.34+6.83

<0.005

HOMA-R

3.79+2.91

4.09+4.54

n.s.

HOMA-B

18.33+15.59

35.05+42.71

<0.005

BMI

25.22+4.63

25.41+4.56

n.s.


 

Table II A2): TG changes in sitagliptin group


 

baseline

3 months

p-values


normal TG
(<199 mg/dl)

117.6+45.1

138.0+70.4

n.s.

high TG
(>200mg/dl)

469.9+256.7

315.5+241.0

<0.001


 

Table II B): Alogliptin


 

baseline

3 month

p-values


FBS (mg/dl)

221.4+53.7

192.3+60.5

<0.02

HbA1c (%)

10.40+2.08

8.80+2.32

<0.00001

T-C (mg/dl)

240.8+40.8

225.7+38.5

<0.02

TG (mg/dl)

209.0+220.0

171.9+131.0

n.s.

HDL-C (mg/dl)

52.4+17.9

53.2+13.2

n.s.

nonHDL-C (mg/dl)

188.4+41.0

172.5+39.0

<0.005

LDL-C (mg/dl)

155.9+52.4

145.1+45.5

<0.05

FFA (eEq/l)

0.808+0.300

0.722+0.277

n.s.

UA (mg/dl)

4.81+1.47

5.45+1.65

<0.00001

insulin (µU/ml)

8.03+6.02

9.52+7.27

0.0052

HOMA-R

4.48+3.51

4.67+3.92

n.s.

HOMA-B

20.26+20.00

30.87+25.35

<0.001

BMI

26.51+5.84

26.52+5.66

n.s.


Kutoh et al.Journal of Diabetes Research and Clinical Metabolism  2012 1:17DOI : 10.7243/2050-0866-1-17