Table 8: b-systems variable-based model search for gene KIF1B
Models are directed systems.  There are 25 models at each level; “(n models)” means n equivalent models, not listed. LR and p are likelihood ratio and significance relative to the IV:Z reference; pincr is incremental significance relative to the immediate model ‘ancestor’. Good models have low H, Δdf, p, pincr, and high ΔLR, %I, ΔAIC, ΔBIC.


Model

Level

H

Δdf

ΔLR

p

%I

ΔAIC

ΔBIC

pincr

IV:XZ:YZ:MZ (25 models)

3

7.46

12

60.3

0.000

32.7%

36.3

7.1

0.077

IV:XZ:YZ (25 models)

2

7.53

8

51.9

0.000

28.1%

35.9

16.4

0.000

IV:XZ (5 models)

1

7.66

4

36.9

0.000

20.0%

28.9

19.2

0.000

IV:WZ (3 models)

1

7.67

4

35.2

0.000

19.1%

27.2

17.5

0.000

13 other models

 

 

 

 

 

 

 

 

 

IV:YZ (4 models)

1

7.86

4

14.0

0.007

7.6%

6.0

-3.7

0.007

IV:Z

0

7.98

0

0.0

1.000

0.0%

0.0

0.0

0.000

 

 

 

 

 

 

 

 

 

 

Model selection criteria

 

 

 

 

 

 

 

 

 

i. Best Model(s) by ΔBIC:

 

 

 

 

 

 

 

 

 

   IV:XZ

1

7.66

4

36.9

0.000

0.1999

28.9

19.2

0.000

ii. Best Model(s) by %I with p < 0.05 and also all pincr  < 0.05:

 

 

 

 

   IV:XZ:YZ

2

7.53

8

51.9

0.000

0.2811

35.9

16.4

0.000

iii. Best Model(s) by ΔAIC:

 

 

 

 

 

 

   IV:XZ:YZ:MZ

3

7.46

12

60.3

0.000

32.7%

36.3

7.1

0.077

iv. Best Model(s) by %I with p < 0.05:

 

 

 

 

 

 

   IV:XZ:YZ:MZ

3

7.46

12

60.3

0.000

32.7%

36.3

7.1

0.077

Zwick et al.Journal of Molecular Engineering and Systems Biology  2012 1:4DOI : 10.7243/2050-1412-1-4