Original ResearchOpen Access
PCI-24781 (abexinostat), a novel histone deacetylase inhibitor, induces reactive oxygen species-dependent apoptosis and is synergistic with bortezomib in neuroblastomaGiselle Saulnier Sholler, Erika A. Currier, Akshita Dutta, Marni A. Slavik, Sharon A. Illenye, Maria Cecilia F. Mendonca, Julie Dragon, Stephen S. Roberts, Jeffrey P. Bond
Applied Scientific Reports 2013 2 : 21 ( 28 December 2013 )
Journal of Cancer Therapetics & Research Open access Journal covers special section Cancer stem cells aims to publish research on identification, characterization and isolation of cancer stem cells in various cancer types, metastatic mechanisms, surface markers and their role in cancer initiation, progression and maintenance. The scope of the section includes reviews, hypothetical theories, clinical practices and novel techniques in regulating cancer stem cells.
Journal of Cancer Therapetics & Research Open access Journal covers special section Innovative Therapies focuses on the treatment and prevention of cancer. This section inculdes cancer curing therapies and pharmaceutical applications with the study of anti-cancer drugs, therapeutic agents and Drug Development based on the signalling mechanisms and pharmacodynamics.
Journal of Cancer Therapetics & Research Open access Journal contains special section Carcinogenesis covers the study of cells undergoing carcinogenesis with uncontrolled mutagenesis. It includes every aspect of biochemical mechanisms in relation to the cancer development. Also the focus is on medicinal research from diagnostic testing to monitoring of tumor progression through modulating agents and molecular epidemiology, examination of cells and tissues.
Journal of Cancer Therapetics & Research Open access Journal covers special section Organ Specific Cancers, With its heterogenetic ability, Cancer has a diversified nature in relation to the organ specificity. This section encompasses study of cancer dvelopment in different organs and their transition among the organs. The primary focus is on heterogeneity, origin, metastasis, angiogenesis and organ specified mechanisms in cancer cells.
Journal of Cancer Therapetics & Research Open access Journal covers special section Radiation and Imaging section includes medical diagnostic procedures and treatment using radiation, chemotherapy and imaging technology. It focuses on the modified therapeutic strategies to control cancer and implementing preventional methods.
Journal of Cancer Therapetics & Research Open access Journal covers special section Epidemiology Genetics and Genomics aim to attract papers in the field of epidemiology, genetics and genomics in cancer cells and cancer patients. Understanding the cancer genetics, gene expression and regulation in cancer cells, their heterogeneity will give new insights in diagnosis and treatment. The section intend to disseminate information and knowledge that may furnish novel applications such as personalized treatment with either DNA or protein kinase targeted drugs, combinations with modern radiotherapeutic approaches. The section also considers studies performing whole genome sequencing to recognize potential drug targets or limited for selected genes to identify patients responding to particular treatments more likely.