Table 2 : Median histological variables evaluated at day 7 after the inoculation of Bothrops moojeni venom in mice treated with 10% of leaf extracts of Cassia occidentalis in lanette cream (EF).


Histological variables  Lanette cream P

  C. occidentalis(-) C. occidentalis(+)  

Necrosis 3,0a 3,0 a 0,28
Oedema 0,0 a 0,0 a 0,44
Hyperaemia 1,0 a 1,0 a 0,26
Haemorrhage 3,0 a 3,0 a 0,43
Polymorphonuclear inflammatory infiltrate 2,5 a 3,0 a 0,14
Infiltration of fibroblasts 2,0 a 1,0 a 0,12
Vascular proliferation 1,0 a 2,0 b 0,032*

(p = level of significance. Different letters differ significantly (Kruskal-Wallis, Dunn's post-test, * p <0.05)
(-) Without plant extract
(+) With plant extract

Borges Delmut et al.Journal of Pharmaceutical Technology and Drug Research  2013 2:10DOI : 10.7243/2050-120X-2-10