Table 1 : Sample investigated, sample codes and compositions. Composition is given in % (w/w), samples were made up to 100.0% with water.


group sample composition (% - w/w)

    solid lipid Miglyol 812 menthol stabilizer

A A1 Softisan® 154 10.0% 8.0% 4.0% TegoCare®450 1.8%
A2 Dynasan® 118 7.0% 7.0% 6.0% TegoCare®450 1.8%
A3 Dynasan® 118 8.0% 6.0% 6.0% TegoCare®450 1.8%
A4 Dynasan® 118 9.0% 7.0% 4.0% TegoCare®450 1.8%
A5 Softisan® 154 10.2% 6.8% 3.0% TegoCare®450 1.0%
A6 Softisan® 154 10.2% 6.8% 3.0% Tween® 80 1.0%
A7 Softisan® 154 10.0% 8.0% 2.0% PlantaCare® 2000 UP 1.8%
A8 Softisan® 154 10.2% 6.8% 3.0% PlantaCare® 2000 UP 1.0%
A9 Dynasan® 118 9.0% 9.0% 2.0% PlantaCare® 2000 UP 1.8%
A10 Softisan® 154 7.0% 0.0% 3.0% TegoCare®450 1.8%

B B1 Softisan® 154 10.0% 8.0% 2.0% TegoCare®450 1.8%
B2 Dynasan® 118 10.0% 8.0% 2.0% TegoCare®450 1.8%
B3 Dynasan® 118 9.0% 9.0% 2.0% TegoCare®450 1.8%
B4 Dynasan® 118 8.0% 8.0% 4.0% TegoCare®450 1.8%
B5 Softisan® 154 8.0% 0.0% 2.0% TegoCare®450 1.8%

C C1 Softisan® 154 10.2% 6.8% 3.0% Pluronic® F68 1.0%
C2 Softisan® 154 10.2% 6.8% 3.0% Inutec® SP1 1.0%
C3 Softisan® 154 10.0% 0.0% 0.0% TegoCare®450 1.8%
C4 Softisan® 154 15.0% 5.0% 0.0% Tween® 80 1.8%

M Keck et al.Journal of Pharmaceutical Technology and Drug Research  2013 2:17DOI : 10.7243/2050-120X-2-17