Figure 5 : Influence of HL-Ns on in vivo biodistirbution of POH-Ns. (A) Semiquantitative analysis of fluorescence clearance in the liver (n = 3) (B) Semiquantitative analysis of fluorescence clearance in the kidney (n = 3). *p < 0.05. (C) Stability of POH-Ns under incubation with serum at 37°C. POH-N probes were incubated for indicated times in 50% FCS-PBS at 37 °C. Samples resolved by SDSPAGE were fluorescently scanned by IVIS Spectrum with excitation filter: 710 ± 15 nm, emission filter: 800 ± 10 nm for POH-P and POH-I or emission filter: 780 ± 10 nm for POH-A.

Kizaka-Kondoh et al.Journal of Pharmaceutical Technology and Drug Research  2013 2:2DOI : 10.7243/2050-120X-2-2