Figure 4 : Cellular safety of methacrylate-based polymers in HeLa cells in the presence and absence of pDNA.

Nanoparticles were formed in PBS or SFM with and without 1 μg of pAcGFP1-C1 using polymer compositions equivalent to N/P=1, 2
and 4, respectively. HeLa cells were incubated for 4 hrs in SFM with nanoassemblies fabricated with pHPMAb- pDMAEMA (Panel A)
and ERL (Panel B). Cell viability was quantified 48 hrs post-treatment using the 2 CellTiter- Glo® assay. Results are normalized to
media control and shown as mean±SD (n=3). *Significantly different (p<0.05).

Pauletti et al.Journal of Pharmaceutical Technology and Drug Research  2014 3:2DOI : 10.7243/2050-120X-3-2