Journal of Pharmaceutical Technology & Drug Research

Journal of Pharmaceutical Technology &
Drug Research

ISSN 2050-120X
Short report

Bacterial growth in media mimicking the high salt and alkalinity of extreme kazakhstan environments results in production of antimicrobial compounds in soil actinomycetes isolated from these extremophile locations

Jill Roberts1, Lyudmila Trenozhnikova2, Lylah Seaton3, Ami Patel3, Colton Faza3, Jacqueline Whitaker4, Christen Mayer4 and Azliyati Azizan3*

*Correspondence: Azliyati Azizan aazizan@health.usf.edu

3. Department of Global Health, USF College of Public Health, Tampa, Florida, USA.


Author Affiliations

1. Department of Environmental and Occupational Health, USF College of Public Health, Tampa, Florida, USA.

2. Institute of Microbiology and Virology, Almaty, Kazakhstan.

4. Florida Hospital, Tampa, Florida, USA.

Abstract

Increasing antibiotic resistance among multidrug resistant pathogens necessitates the search for newer antimicrobials. Streptomyces historically produce the largest number of antibacterials and herein we describe isolation of antagonists from extremophiles using unusual culture media. Antagonists or antimicrobials produced under extremophile environmental conditions demonstrated activity against MRSA from Kazakhstan and the United States.

Keywords: Extremophiles, antagonists, antibacterial, antibiotics, HA-MRSA

ISSN 2050-120X
Volume 2
Abstract Download