2. Intern, Bharati Vidyapeeth Dental College and Hospital, Pune, Mahrashtra, India.
3. Director, My Dentist, Mumbai, India.
Engineering of craniofacial tissues would have a profound impact on various treatment strategies in dentistry. The role of mesenchymal stem cells in the formation of all craniofacial and dental structures has been well demonstrated. Stem cells from various craniofacial structures like dental epithelium, dental follicle, apical papilla, exfoliated deciduous teeth, periodontal ligament and dental pulp are readily accessible and have immense potential in craniofacial research for regenerative and tissue engineering applications. Various signalling molecules that pattern the morphogenesis of craniofacial tissues have been explored. This review article epitomises how dentistry should evolve and highlights the need for close partnerships between basic and clinical scientists.
Keywords: Tissue engineering, dentistry, stem cell, dental papilla, dental follicle, dental pulp stem cells