Table 1 : Biochemical tests and in vitro protein binding
of AS and DHA in control and DM rats.


  Control DM P value

Biochemical parameters

Body weight (g) 262.4±1.2 215.3±1.9 0.004
BS (mg/dL) 145.1±4.8 561.3±9.9 0.004
Alb (g/dL) 3.86±0.06 3.76±0.04 0.792
GA (g/dL) 0.53±0.01 1.09±0.03 0.004
TP (g/dL) 5.22±0.07 4.97±0.05 0.429

Protein bindinga

AS (%) 83.7±0.4 86.2±0.7 0.200
DHA (%) 92.6±0.2 92.2±0.2 0.686

BS: blood sugar. Alb: albumin. GA: glycoalbumin. TP: total protein.
Each value represents the mean ± S.E. of control (n=5) and
DM (n=6) rats for biochemical parameters, and control (n=4)
and DM (n=4) rats for protein binding. aprotein binding studies
were performed at a nominal concentration of 0.4 μg/mL
Differences in the means were tested using the
Mann-Whitney U test.

Sugioka et al.Interactive Medicinal Chemistry  2014 2:1DOI : 10.7243/2053-7107-2-1