Table 3 : Correlation of DNA-ploidy on biopsies with extracapsular spread (ECS) after radical prostatectomy (RPE).


  Year Journal Number of
patients investigated
Months
follow-up
Significance p Flow/Image
cytometry

Oxford level 1b

Isharwal et al., [167] 2009 J Urol 370 5 <0.001
  AUC-ROC+1.5%
ICM
Brinker et al., [168] 1999 J Urol 159 -- 0.003 ICM
Vesalainen et al., [169] 1994 Br J Cancer 273 187156 <0.0001 FCM
Ross et al., [170] 1994 Cancer 89 18731.2 0.04 ICM
Green et al., [171] 1994 J Urol 70 -- <0.0001 ICM
Häggmann et al., [172] 1994 Scand J Urol Nephrol 54 -- <0.0001 ICM
Ross et al., [173] 1994 Mod Pathol 56 18728.8 0.03 ICM
Badalament et al., [174] 1991 Cancer 112 -- 0.04 FCM

Bold p-values refer to Cox multivariate regression analysis.

Böcking et al.Pathology Discovery  2014 2:7DOI : 10.7243/2052-7896-2-7