Table 7 : Correlation of DNA-ploidy with local recurrence or progress.


Authors Year Journal Number of patients Months of follow-up Significance Flow/Image
Cytometry
Comment

After RPE

Oxford level 2b

Ross et al., [225] 1999 Am J Surg Pathol 111 27 0.002 ICM --
Ross et al., [170] 1994 Cancer 89 31.2 <0.001 ICM 3 x more frequent
Zincke et al., [182] 1992 Cancer 370 60 <0.0001 FCM Plus hormonal treatment
Montgomery et al., [190] 1990 Arch Surg 283 112.8 <0.001 FCM Stage B
Winkler et al., [186] 1988 Mayo Clin and
Foundation
91 >60 <0.0001 FCM Stage D1

After hormonal therapy

Oxford level 2b

Eskelinen et al., [227] 1991 Eur Urol 35 187 0.028 FCM T1/2

After brachytherapy

Oxford level 2b

Keyes et al., [223] 2013 In J Rad Oncol
Biol Phys
94 90 0.011 ICM PSA recurrence

Bold p-values refer to Cox multivariate regression analysis.

Böcking et al.Pathology Discovery  2014 2:7DOI : 10.7243/2052-7896-2-7