Figure 1 : (a,b) Time course of the effects of 1% ethanol on the amplitude of the ERG b- and d-wave.

Results of both control experiments (open symbols) and test experiments of main group (filed symbols) are represented. The amplitude of the ERG waves is normalized to the values obtained just prior ethanol application. The time, when the perfusion was switched to 1% ethanol solution (EtOH), is indicated by an arrow. Mean values ±SEM are shown. (c) Dose-response relationship for ethanol effects on the b- and d-wave amplitude. The amplitude of the ERG waves during treatment with 3 different concentrations of ethanol (0.25%, 0.5% and 1%) are compared to the corresponding values obtained in the control experiments (0% ethanol). The statistical significance of the obtained differences is denoted as: **p<0.01; ***p<0.005; ****p<0.0001. (d) Original ERG records (b- and d-wave), obtained during the perfusion with Ringer solution in the control period (upper row), 1% ethanol (middle row) and Ringer solution in the recovery period (bottom row) . Calibration: time –0.2 s; amplitude –50 μV.

Popova et al.Journal of Psychiatry and Brain Functions  2015 2:6DOI : 10.7243/2055-3447-2-6