Journal of Allergy and Asthma

Journal of Allergy and Asthma

ISSN 2054-9873
Case report

The Forgotten “Weed” Allergy: A Case Report of Fresh-Food Skin Prick Testing as a Model for Evaluating Allergy in a Patient with Cannabis-Induced Urticaria

William Keefe1†, Justin Chin2*† and Mary Lee-Wong3,4†

*Correspondence: Justin Chin

1. Mount Sinai Beth Israel Medical Center, Department of Internal Medicine, New York NY-USA.

†These authors contributed equally to this work.

Author Affiliations

2. Lifelong Medical Care, Department of Family Medicine, Richmond, CA-USA.

3. Mount Sinai Beth Israel Medical Center, Chief of Allergy and Immunology, Department of Internal Medicine, New York NY-USA.

4. Icahn School of Medicine at Mount Sinai, Clinical Associate Professor of Medicine, Department of Medicine, New York NY-USA.


Background: Cannabis sativa, more commonly known as marijuana, use has steadily increased in the past decade with increasing decriminalization and acceptance among the United States population. More than 20% of Americans state that they have either tried or currently use marijuana in their lifetime. Subsequently, the rates of allergic reactions associated with cannabis handling, ingestion, and utilization have also risen by association.

Case Presentation/Methods: 53-year-old Black male presented to the outpatient allergy clinic with a case of suspected cannabis induced urticaria status post contact with dried cannabis, with red raised rashes. The rashes would appear whenever he handled dried cannabis and spontaneously self-resolve. Due to the lack of formal guidelines in cannabis allergy testing, he was evaluated using fresh-food skin prick testing, which revealed positive reaction to his cannabis sample. Management and counseling were provided to the patient in regards to allergy prophylaxis and symptom treatment.

Discussion/Results: Increasing prevalence of cannabis allergies have informed the contemporary need to develop standardized protocols for testing. The lack of commercially-prepared skin prick testing necessitated the creation of a fresh-food derived skin prick testing protocol for this patient.

Conclusion: Limited research and testing protocols currently exist for the diagnosis and treatment of cannabis allergies due to continuing federal restrictions and ethical considerations. As cannabis use becomes more commonplace, the development of standard procedures is necessary to ensure that patients are being adequately assessed.

Keywords: Cannabis, marijuana, allergy, fresh food testing, skin prick testing

ISSN 2054-9873
Volume 7
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