Cardiovascular System

Cardiovascular System

ISSN 2052-4358
Case report

Systemic Lp-PLA-2 cardiovascular marker response to direct medication delivery periodontal treatment

Duane C. Keller

Correspondence: Duane C. Keller

Author Affiliations

St Louis Health and Wellness Keller Professional Group, St Louis, USA.


Periodontal disease has been associated as a co-contributor for cardiovascular disease. Inflammatory markers such as lipoprotein-associated phospholipase A2 (Lp-PLA2) demonstrate an increased risk of heart attack and ischemic stroke. It is not known to what extent treating periodontal disease may affect changes in Lp-PLA2 levels. This case report discussed treating patients periodontal conditions with the Perio Protect Method (PPM) and evaluating systemic Lp-PLA2 levels, before, during and after periodontal treatment. This pilot study demonstrates that treating the patient’s periodontal conditions resulted in decreasing the periodontal markers and lowering the Lp-PLA2 levels and these findings may be important as an adjunct of cardiovascular treatment.

Keywords: Periodontal disease, Lp-PLA2, cardiovascular disease, perio tray, perio protect method

ISSN 2052-4358
Volume 2
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