Table 3 : Genes absent in non-O1 Vibrio cholerae genome and present in O1 V. cholerae genome.


Description Abbreviation N16961 Accession N16961

Accessory cholera enterotoxin* ace P38441
Cholera enterotoxin subunit B* ctxB P01556
Cholera enterotoxin subunit A* ctxA P01555
Zona occludens toxin* zot P38442
Toxin coregulated pilus biosynthesis protein F* tcpF P0C6Q5
Toxin-coregulated pilus biosynthesis protein P tcpP Q7BGC9
Toxin coregulated pilus biosynthesis protein I tcpI P0C6D8
Toxin coregulated pilus biosynthesis protein H tcpH P29489
Toxin coregulated pilus biosynthesis protein B tcpB P23476
Toxin coregulated pilus biosynthesis protein E tcpE P0C6C9
Transcriptional activator protein NhaR nhaR P52692
Outer membrane lipoprotein blc blc Q08790
ATP synthase protein I atpI Q9KNG8
Type 4 prepilin-like proteins leader peptide-processing enzyme§ tcpJ P0C6D9
N5-carboxyaminoimidazole ribonucleotide synthase§ purK Q9KVT8
Coproporphyrinogen-III oxidase§ hemF Q9KVT4
Aldehyde dehydrogenase§   aldA P0C6D7
Putative N-acetylmannosamine-6-phosphate 2-epimerase§ nanE Q9KR62
N-acetylmannosamine kinase§ nanK Q9KR61
N-acetylneuraminate epimerase§   nanM Q9KR69
N5-carboxyaminoimidazole ribonucleotide mutase§ purE Q9KVT7
Ribosome modulation factor||  Rmf Q9KRZ9
Accessory colonization factor AcfA* VC_0844 H9L4S5
Accessory colonization factor AcfB* VC_0840 Q9KTQ7
TagE protein* VC_A1043 Q9KKQ9
TagE protein* VC_0843 H9L4P5
Uncharacterized protein VC_1460* VC_1460 P38443
Fimbrial biogenesis and twitching motility protein, putative VC_1612 Q9KRM4
Type IV pilin, putative VC_0858 Q9KTP3
Fimbrial protein VC_2423 Q9KPE5
Fimbrial assembly protein VC_2630 Q9KNV0
Putative uncharacterized protein VC_1703 Q9KRD9
RTX toxin transporter VC_1448 Q9KS14
Uncharacterized protein similar to VCA0109 VC_A0109 Q9KN56
C4-dicarboxylate transport protein DctQ, putative VC_1928 Q9KQS0
Trk system potassium uptake protein VC_0042 Q9KVU7
PTS system, cellobiose-specific IIC component VC_1282 Q9KSH4
Multidrug resistance protein VceB VC_1411 Q9KS49
Iron(III) compound receptor VC_0200 Q9KVE6
Sugar transporter family protein VC_A0669 Q9KLS2
Potassium uptake protein TrkA VC_0043 Q9KVU6
Multidrug resistance protein, putative VC_1409 Q9KS51
Sodium/solute symporter VC_A0667 Q9KLS4
C4-dicarboxylate-binding periplasmic protein VC_1779 Q9KR64
Multidrug resistance protein D VC_A0214 Q9KMV4
Multidrug resistance protein D VC_A0267 Q9KMQ3
PTS system, N-acetylglucosamine-specific IIABC component VC_0995 Q9KTA8
Lipopolysaccharide/O-antigen transport protein VC_0246 Q9KVA3
Iron(III) ABC transporter, permease protein VC_0203 Q9KVE3
Putative uncharacterized protein VC_A0716 Q9KLM7
Multidrug resistance protein VceA VC_1410 Q9KS50
Putative uncharacterized protein VC_A0355 Q9KMJ3
Helicase, putative§ VC_1760 Q9KR83
DNA-damage-inducible protein J§ VC_A0324 Q9KML3
N-acetylglucosamine-6-phosphate deacetylase§ VC_1783 Q9KR60
Sigma-54 modulation protein, putative|| VC_2530 H9L4N9

Included in this table are genetic elements that are absent in the non-O1 genome but present in the O1 genome, which
have putative functions in virulence, disease and defense, membrane transport, DNA metabolism and dormancy and
sporulation. In the table, the first column includes gene descriptions as per UniProt. Second and fourth columns
represent abbreviated gene identification; the third and fifth columns represent accession numbers for the listed genes.
The symbol (*) denotes proteins that have functions in virulence, disease and defense. The symbol () includes
proteins that are putative membrane transporters. Symbols (§) and (||) include proteins that have putative functions in
DNA metabolism and dormancy/sporulation categories, respectively.

Varela et al.Genomics Discovery  2014 2:1DOI : 10.7243/2052-7993-2-1