Table 2 : Outcome and complication of the transvaginal mesh procedure for pelvic organ prolapse surgery with synthetic polypropylene mesh.


Author/Study Number of patients Complications Comments

Julian case control study [19] 24 25%mesh erosion and infection Safe and effective
Fatton et al., [20] 110 4.7% mesh erosion, 2.8%granuloma Procedure effective and safe
Altman et al., [21] 123 1 0% bladder perforation,
5% rectal perforation, 1%  bleeds>1000cc
Secondary outcome reported inconsistently
Sola et al.,[22] 41 3.2% injury, 3 bladder injury and 1 rectal injury Secondary outcome reported inconsistent
Van raalte et al.,[23] 46\anterior, 280posterior,   23both 1% mesh  extrusion, 1%  perirectal hematoma Less complication
Hinoul et al., [24] 48 anterior 10.5% extrusion, 15% prolapse in untreated compartment No mesh erosion
Iglesia et al., (RCT)[25] 24 10.5% extrusion
15% dyspareunia
Mesh extrusion reported earlier
Cosson et al., [26] 687 15.6% mesh erosion, 12.5%- reoperation Number needed to treat
Kdous et al., [27] 45 - -
Luisa A et al., [28] 68 2 dyspareunia, 1 mesh exposure, 4  vaginal discharge,
3 granulation, 6 tenderness over graft
-
Laurent de Landshree et al., [29] 48-anterior, 103-posterior, 373both compartment 3 bladder perforation, 1 rectal injury,
3 urinary incontinence, 19 mesh erosion, 14 mesh exposure,
48-anterior, 103-posterior, 373both compartment
The Nordic TVM group [30] 123 2 mesh exposure, 3 bladder injury, 1 rectal injury Overall minimal complication
m.abdel Fattah et al.,[31] 70-anterior, 70 posterior, 70-both compartment 14 urinary stress incontinence, 23 prolapsed in another compartment,
3 bladder injury, 2 rectal injury, 6 blood loss>400ml.,
30 vaginal erosion, 3 vaginal adhesion
Secondary outcome report inconsistent
De tayrac et al.,[32] 32 9.1% mesh erosion
5.5% mesh related pain
Number needed to treat 4
Milani et al., [33] 32 13% mesh erosion -
Hiltunen (RCT) [34] 19 - effective
Maher et al., (RCT) 2011[35] 55 9% -
Withagen et al.,. (RCT) 2011 [36] 93 16.9% Elderly pt. rise risk of UTI and urgency
Nieminen et al., (RCT)[37] 105 Stress urinary incontinence, 1.7%,
dyspareunia, 19% mesh erosion
-
Eva m. de. Cuyper [38] 64 4 dyspareunia, 3 mesh erosion, 4 urgency, Less complication seen
Handel et al., [39] 25 - 100% success
Vincent letouzey et al., 2010 France [40] 63 2 dyspareunia, 8 stress urinary incontinence,
10 urgency, 9 mesh erosion, 1 fecal incontinence
Primary outcome measure inconsistent
Yan et al.,[41] 30 1 post operative urinary retention, 5 dyspareunia,
2 incontinence, 1 mesh erosion
Less postoperative complication
Von Theobald & lube.   (Retrospective study, France) [42] 92 1 hematoma, 3 vaginal erosion effective
Young Suk Lee [43] 49 1 vaginal erosion, 2 posterior vaginal prolapsed effective
Migliarie et al.,[44] 12 No mesh related complication 100%success
Dwyer and o’reilly [45] 50 12%-mesh erosion, 1 rectovaginal fistula High rate of mesh erosion
Bai et al., (prospective cohort)[46] 28 Undefined -
Fikret faith onol et al.,[47] 118 8 stress urinary incontinence, 10 dyspareunia,
10 mesh extrusion, 11 vaginal erosion
Megsh erosion and extrusion average
Salvatoe et al., 2002 [48] 31 6 dyspareunia, 3 infections, effective
Mercer jones et al.,[49] 22 2 rectal perforation, 13% mesh erosion Inadequate method
Palma et al., 2008[50] 18 UTI Safe and effective
Watson et al., [51] 9 No mesh related complication 100% success, but less data
Montironi et al., Italy[52] 35 1 vaginal erosion Safe and effective
Scott serels et al.,[53] 63 18  urge incontinence Infection moreover
Smith ARB et al., [54] 36 2 mesh erosion success
Petros pe et al., [55] 36 - -
Moore RD et al., [56] 61 7%  urinary retention Postoperative care inadequate
Alinsod R et al., [[57]] 76 4 Voiding difficulty Most effective
Meschia M et al.,[58] 91 Recurrent UTI, dyspareunia Infection other than mesh related
Beer and Kuhn [59] 55 2.3%hematoma, 2.9% urological problem,
0.8% damage to pelvic wall, 1.8% damage to nerve
Operative skill
Karen l et al.,[60] 102 4 bladder perforation, 5-mesh erosion,
2 recurrent incontinence, 6  de Novo urge loss, 10 failure
Less complication
A. Ranganathan et al.,[61] 81 4 persistent urinary incontinence, 2 de Novo overactive bladder Less complication

Guiying et al.Gynecology  2013 1:4DOI : 10.7243/2052-6210-1-4