Figure 1 : Clinical course timeline showing major chromosomal abnormalities and clonal evolution.

The clinical course is based on histopathologic diagnoses on bone marrow specimens from 2007 at an outside institution until January 2016. Complex BCR/ABL1: t(9;15;22)(q34;p10;q11.2), typical BCR/ABL1: t(9;22)(q34;q11.2) does not have the “complex” prefix. Note the presence of chromosomal abnormalities during remission and clonal evolution.

Zaslav et al.Hematology and Leukemia  2016 4:2DOI : 10.7243/2052-434X-4-2