Figure 4 : G-banded metaphase from analysis #8:45,XX,der(5)t(5;?),t(9;22)(q34;q11.2),-15,der(22)t(9;22)(q34;q11.2)t(15;22)(q23;q11).

The der(22) has BCR/ABL1 translocated to the long arm of the der(22) and PML (15q23) translocated to the short arm of the der(22). The arrows indicate the derivative chromosomes 9 and 22 and the missing chromosome 15 homolog (left panel). Top right panel reverse-DAPI image demonstrates the BCR/ABL1 translocation on the long arm of the der(22). Arrows indicate the normal chromosome 9 (red), the normal chromosome 22 (green), the der(9) (yellow) and the der(22) (yellow). Bottom right panel reverse-DAPI image demonstrates PML (15q23)(green) on the short arm of the der(22). Arrows indicate the normal chromosome 15 and the der(22).

Zaslav et al.Hematology and Leukemia  2016 4:2DOI : 10.7243/2052-434X-4-2