2. Specialization Board, Khartoum, Sudan.
3. Department of microbiology, Princess Nora bint Abdulrahman University in Riyadh Princess Nora bint Abdulrahman University in Riyadh.
4. School of Pharmacy and Biomedical Sciences, Portsmouth University, UK.
A haemoglobin (Hb) disorder was the first polymorphism suggested to have a relationship with malaria, as Hb S and C offer a survival advantage in malarial endemic regions. Two schoolgirls aged 11 and 16 were admitted to the Military Hospital in Omdurman on the 2nd of April 2009. They had Hb (haemoglobin) SC and their parents were carriers of abnormal Hb; the mother was (HbAS) and father (HbAC). These girls were the first reported cases of HbSC in Sudan. Capillary Electrophoresis (CE) was initially used to determine the Hb type. CE-High Performance Liquid Chromatography (CE-HPLC) was used as a confirmatory test. A new type of abnormal Hb in Sudan is not unexpected, because is of its wide tribal diversity. Additionally, Sudan is a high malarial region and a new Hb variant is likely to be discovered.
Keywords: Hb S and C, haemoglobinopathies management and population