Figure 2 : (A) A photomicrograph of transverse section of adult albino rat testis of group A showing spermatogonia A (A) and B (B) rest on defined basal lamina(M).

Notice the presence of primary spermatocyte(P), early spermatid(E), late spermatid(L) and sertoli cells (S), spermatozoa(z). The interstitial cells of leydig (I) appear between the seminiferous tubules.
(B1) A photomicrograph of transverse section of testis of adult albino rat of group B showing marked deterioration of the seminiferous tubule. The basal lamina (M) of seminiferous tubules appears distorted and detached. Most of spermatogenic cells have vacuolated cytoplasm (black arrow). Some of their nuclei (N) appear deeply stained and irregular. Notice the presence of intercellular space (star) between the spermatogenic cells. Notice also the presence of eosinophilic material between the seminiferous tubules (green arrow). The interstitial cell of leydig (I)appears dispersed.
(B2)A photomicrograph of transverse section of testis of adult albino rat of group B showing that most of spermatogenic cells have vacuolated cytoplasm (black arrow). Some of their nuclei appear deeply stained and irregular (N). Notice the presence of intercellular space (red star) between the spermatogenic cells. Notice also the absence of sperms in the lumen of the seminiferous tubules.
(C) A photomicrograph of transverse section of testis of adult albino rat of group C showing mild deterioration of seminiferous tubules. The basal lamina (M) appears continuous and regular. Most of the spermatogonia A(A), spermatogonia B (B), Sertoli cells (S), primary spermatocytes (P), early spermatid(E) and late spermatid (L) are more or less similar to that of group A. Some spermatogenic cells have vacuolated cytoplasm(black arrow) while few of them have deeply stained nucleus(yellow arrow). The interstial cells of leydig (I) appear nearly similar to that of group A.

Mohamed et al.Journal of Histology & Histopathology  2015 2:21DOI : 10.7243/2055-091X-2-21