Figure 1 : (a) H&E (x4) from a case of follicular lymphoma.

with (b) higher power (x20) of a neoplastic follicle (Grade 1-2) (c) H&E (x40) of a diffuse large B-cell lymphoma case (d) Low MIB1 proliferation index (4%; x10) (e) Intermediate MIB1 proliferation index (48%; x10) (f) High MIB1 proliferation index (99%; x10) - the area circled in green were selected by the reviewing pathologist for digital quantification by the computer algorithm.