journal of Histology & Histopathology

Journal of Histology & Histopathology

ISSN 2055-091X
Case report

Well differentiated thyroid tumor of unknown malignant potential (WDT UMP) associated with COWDEN syndrome

Enaam Junainah*, Mohammed AlShanbari, Nashat Gandoura, Nadia Enani, Khalid Alnouri, Sahar Fatta, Jamal Junainah, Abdulelah Sber, Saeed Alamoudi, Manal Junainah and Fawzi Junainah

*Correspondence: Enaam Junainah

Author Affiliations

Departments of Pathology, King Fahad general Hospital, Jeddah, Saudi Arabia.


Cowden syndrome is a rare cancer predisposition syndrome inherited in an autosomal-dominant fashion. The syndrome is characterized by hamartomatous polyps that affect multiple organs: skin, mucous membranes, thyroid, breast, gastrointestinal tract, endometrium and brain. It is also associated with an increased risk of developing malignancy in many tissues but especially breast, thyroid and endometrium. Thyroid tumor is ranging from benign nodule to frank malignancy. We report a case of WDT UMP in 66 years old lady who has CS.

Keywords: WDT UMP, COWDEN syndrome, thyroid tumor

ISSN 2055-091X
Volume 1
Abstract Download