Figure 1 (a and b) : Mechanism of action of HDAC inhibitors in oncology applications.

A schematic representation of the possible mechanism of actions of HDAC inhibitors in rendering local tumor control (when used as a single therapeutic agent) and in synergizing with radiation or chemotherapeutic agents when used in combination therapies.

K Agrawala et al.HOAJ BIOLOGY  2013 2:2DOI : 10.7243/2050-0874-2-2