Table 2 : The frequency distributions of SCYA-115 gene polymorphisms in binding sites for transcription factor in susceptible and resistant groups.


Polymorphism locus Susceptible individuals NO.(%) Resistant individuals NO.(%) χ2 (P) OR (95% CI) B (P) Wald

-820 - - - - - -

Allele            

A 29(48.33) 18(30.00) 4.23(0.040a) 2.18 0.78(0.041) 4.17
T 31(51.67) 42(70.00) - (1.03-4.62) - -

Genotype            

A/A 5(16.67) 1(3.33) 5.50(0.064) - - -
A/T 19(63.33) 16(53.33) - - - -
T/T 6(20.00) 13(43.33) - - - -
 HWE χ2(P) 2.16(0.14) 2.18(0.14) - - - -

-752 - - - - - -

 Allele            

ins 8(13.33) 17(28.33) 4.09(0.043) 0.39 -0.94(0.047) 3.94
del 52(86.67) 43(71.67) - (0.15-0.99) - -

Genotype            

ins/ins 1(3.33) 1(3.33) 6.05(0.049) - -0.50(0.73) 0.12
  ins/del 6(20.00) 15(50.00) - - -1.41(0.017) 5.73
del/del 23(76.67) 14(46.67) - - - -
 HWE χ2(P) 0.54(0.46) 1.60(0.21) - - - -

-742 - - - - - -

 Allele            

C 55(91.67) 56(93.33) 0.120(0.73) 0.79 - -
T 5(8.33) 4(6.67) - (0.20-3.08) - -

Genotype            

C/C 25(83.33) 26(86.67) 0.131(0.72) 0.77 - -
C/T 5(16.67) 4(13.33) - (0.19-3.20) - -
 HWE χ2(P) 0.25(0.62) 0.15(0.70) - - - -

-514 - - - - - -

 Allele            

A 53(88.33) 51(85.00) 0.288(0.59) 1.34 - -
G 7(11.67) 9(15.00) - (0.46-3.86) - -

Genotype            

A/A 23(76.67) 21(70.00) 0.341(0.56) 1.41 - -
A/G 7(23.33) 9(30.00) - (0.45-4.45) - -
 HWE χ2(P) 0.52(0.47) 0.93(0.33) - - - -

-413 - - - - - -

Allele            

A 43(71.67) 39(65.00) 0.62(0.43) 1.36 - -
T 17(28.33) 21(35.00) - (0.63-2.95) - -

Genotype            

A/A 15(50.00) 11(36.67) 1.15(0.56) - - -
A/T 13(43.33) 17(56.67) - - - -
T/T 2(6.67) 2(6.67) - - - -
 HWE χ2(P) 0.14(0.71) 1.81(0.18) - - - -

-408 - - - - - -

 Allele            

C 3(5.00) 4(6.67) 0.15(0.70) 0.74 - -
T 57(95.00) 56(93.33) - (0.16-3.44) - -

Genotype            

C/T 3(10.00) 4(13.33) 0.16(0.69) 0.72 - -
T/T 27(90.00) 26(86.67) - (0.15-3.55) - -
 HWE χ2(P) 0.083(0.77) 0.15(0.70) - - - -

OR= odds ratio; B indicated partial regressioncoefficient in logistic regression
aThe distributions in susceptible and resistant groups were significantly different (P<0.05).

He et al.  2013 2:3DOI : 10.7243/2050-0874-2-3