Figure 3 : KCC2 was dephosphorylated and downregulated in the PVN following chronic social
defeat stress.

Representative Western blots of total KCC2 expression (Left) and phosphorylated Ser940 KCC2 expression
(Right) in the PVN of dominant and submissive mice following the chronic social defeat stress paradigm.
The average optical density of total KCC2 expression (Left) and KCC2 residue Ser940 phosphorylation (Right)
was decreased in submissive mice compared to dominant. (n=10 mice per experimental group).
* indicates statistical significance of p<0.05 using a Student’s t-test.

Maguire et al.Hormonal Studies  2014 2:2DOI : 10.7243/2052-8000-2-2