Figure 2 : Time course of receptor activator of nuclear factor-kappa B ligand (RANKL) and osteoprotegerin (OPG) mRNA expression
induced by Escherichia coli (A), Porphyromonas gingivalis (B) and interleukin-1 beta (C) in periodontal ligament cells (mPDL).

Bars indicate mean and standard deviation of density analysis of three independent experiments. Data are expressed as fold change
in unstimulated control group (ctrl) after normalization to GAPDH. In all graphs asterisk (*) indicates significant difference (p<0.05) in
relation to ‘1’ attributed to unstimulated control (ctrl) by one-sample t test. Exclamation mark (!) indicates significant difference
(p<0.05) within the same time point with the other dose of the same agonist by unpaired t test. E. coli, Escherichia coli ; P. gingivalis,
Porphyromonas gingivalis
; IL-1b, interleukin-1 beta; LPS, lipopolysaccharide; GAPDH, glyceraldehyde-3-phosphate dehydrogenase.

GuimarĂ£es et al.Immunology Innovation  2014 2:1DOI : 10.7243/2053-213X-2-1