Journal of Anesthesiology & Clinical Science

Journal of Anesthesiology & Clinical Science

ISSN 2049-9752
Short report

Neutrophil gelatinase-associated lipocalcin (NGAL) as a biomarker of dialysis-dependent acute kidney injury following infrarenal aortic surgery

Helene Korvenius Jørgensen1*, Jannie Bisgaard1 and Torben Gilsaa1

*Correspondence: Helene Korvenius Jørgensen

Author Affiliations

1. Lillebaelt Hospital Kolding, Department of Anaesthesiology and Intensive Care, Denmark.


Background: Acute kidney injury (AKI) is common following abdominal aortic surgery. NGAL might be useful in the early diagnosis of AKI since it responds rapidly to ischaemic damage.

Methods: Twenty patients undergoing elective infrarenal aortic surgery. U-NGAL was measured before surgery and 24, 48 and 72 hours postoperatively.

Results: No significant rise in U-NGAL was seen in patients without AKI at any time. All patients who developed dialysisdependent AKI had a significant increase in U-NGAL.

Conclusion: U-NGAL did not increase solely in response to the surgical trauma. U-NGAL may be a useful biomarker for AKI following abdominal aortic surgery.

Keywords: Acute kidney injury, abdominal aortic surgery, intensive care.

ISSN 2049-9752
Volume 2
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