Figure : 1 Shuttle vectors for adenoviruses containing the arginine variant p53 gene (Shuttle-p53R), the proline variant p53 gene (Shuttle-p53P),
the ERE-linked arginine variant p53 gene (Shuttle- EREp53R), and the ERE-linked proline variant p53 gene (Shuttle- EREp53P). Bases 166–1203
of the p53 genes (indicated by orange lines) were inserted to the 5' side of the green fluorescent protein gene of the shuttle vector, and ERE and
two nucleotides were linked to the 5' end of the start codon for ERE-linked genes.