Figure 2  :  Metronomic chemotherapy reduces the rapid proliferating angioblast-like CEPs (circulating and growing out from bone marrow) and
possibly inhibits proliferating ECs (most of the ECs of `old` vessels do not proliferate). (modified from [126]).

Klaus et al.Journal of Cancer Therapeutics and Research  2012 1:32DOI : 10.7243/2049-7962-1-32