Figure 6 : Baseline contrast-enhanced T1-weighted MR image (A), showing a heterogeneously enhancing irregular mass in the left breast with a centrally placed marker clip. Note the adjacent skin thickening. After completion of neoadjuvant chemotherapy (B), the tumour bed reduced slightly, and limited enhancement was observed in this area. Detailed outtake of this area (C) shows the signal void caused by the marker (*), surrounded by two rims of increased signal intensity (arrows). This might suggest or obscure small foci of residual disease. The configuration of the increased signal intensity parallel to the signal void suggests a susceptibility artifact. The final conclusion of this case was ‘probably complete response, but residual disease cannot be ruled out’. Histopathologic analysis showed complete pathologic response (Miller and Payne grade 5).

Lobbes et al.Journal of Cancer Therapeutics and Research  2012 1:34DOI : 10.7243/2049-7962-1-34