Figure 6 : Potentiation of paclitaxel-mediated G2/M arrest by volasertib in ABCB1-overexpressing SW620 Ad300 cells. 


(A)Parental SW620 and ABCB-overexpressing resistant SW620 Ad300 cells were allowed to expose to paclitaxel (Taxol, 20 nM) alone, volasertib (20 nM) alone, or their combination (V+T) for 24 h before harvest for cell cycle analysis. A representative set of data from three independent experiments is shown. (B) Summary of cell cycle analysis results from three independent experiments. Data are presented in histogram as means + SD. *, p < 0.05; **, p < 0.01, versus the no treatment control in parental SW620 cells.

To et al.Journal of Cancer Therapeutics and Research  2013 2:13DOI : 10.7243/2049-7962-2-13