Figure 3 : N-acetyl-cysteine pretreatment blocks cytotoxicity of PCI-24781 plus bortezomib.
Cells were pre-incubated with 15 mM NAC or vehicle (control), and then treated with 100 nM PCI-24781, 6 nM bortezomib, or both and incubated for 48 hours
followed by cell viability assay (p value <0.005 ).