Table 4 : Hepatic annexin A2 mRNA and annexin A2 immunehistochemical study in chronic hepatitis,
liver fibrosis, liver cirrhosis, early and late hepatocellular carcinoma.
| Group | Annexin A2 mRNA expression by RT-PCR |
P-value | Annexin A2 intensity by immunehistochemistry |
P-value | ||||
| Negative | Positive | - | + | ++ | +++ | |||
| Chronic hepatitis (n=6) | 5 | 1 | P<0.000*** | 5 | 1 | 0 | 0 | P<0.000*** |
| Liver Fibrosis (n=8) | 6 | 2 | 6 | 2 | 0 | 0 | ||
| Liver cirrhosis (n=6) | 3 | 3 | 3 | 2 | 1 | 0 | ||
| Early HCC (n=8) | 0 | 8 | 0 | 2 | 4 | 2 | ||
| Late HCC (n=12) | 0 | 12 | 0 | 0 | 3 | 9 | ||