Abstract

Rituximab is being utilized off-label by physicians for many diseases such as myasthenia gravis, multiple sclerosis, CIDP, and Ig4 related disease such as Idiopathic Hypertrophic Pachymeningitis. Our case illustrates the danger of giving rituximab to an older person who may harbor asymptomatic coronary artery disease and incurring an arrhythmia or myocardial infarction from cytokine release. Our case along with the PI warning of rituximab and numerous other case reports should prompt physicians to obtain cardiology consultation prior to giving rituximab to an older population.

Keywords: Rituximab, cytokine release syndrome, myocardial infarction