Journal of Cancer Therapeutics & Research

Journal of Cancer Therapeutics & Research

ISSN 2049-7962
Case report

Fatal myocardial infarction due to rituximab in the treatment of IgG4 related disease-another case, tip of the iceberg?

James A. Charles*, Richard Righthand and Paul Avenoso

*Correspondence: James A. Charles

Holy Name Medical Center, 718 Teaneck, Rd Teaneck, NJ 07666, USA.


Rituximab is being utilized off-label by physicians for many diseases such as myasthenia gravis, multiple sclerosis, CIDP, and Ig4 related disease such as Idiopathic Hypertrophic Pachymeningitis. Our case illustrates the danger of giving rituximab to an older person who may harbor asymptomatic coronary artery disease and incurring an arrhythmia or myocardial infarction from cytokine release. Our case along with the PI warning of rituximab and numerous other case reports should prompt physicians to obtain cardiology consultation prior to giving rituximab to an older population.

Keywords: Rituximab, cytokine release syndrome, myocardial infarction

ISSN 2049-7962
Volume 7
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